If wisdom and human-self rule...
If wisdom and human-self rule, then the animal-self and his passions are adjusted, optimized, and all of them are mobilized for journeying on the path of exaltedness and perfection leading towards God's Nearness. In this case the human-self which is the same existence attached to God - assumes his authenticity, whereby revival of moral excellence in conduct and God's Nearness become the primary goal, and taking care of one's animalistic requirement will become a secondary aim.
Therefore, egotism and love for self not only has not been condemned, on the contrary have been praised. But if the imperious-self and animal-self took over control of bodily affairs, the wisdom and human-self are subdued and become isolated, in which case a man gradually takes distance from God and human values, falling ultimately into deep and dark valleys of ignorance. He forgets his human-self (i.e. humanism) and recognizes in his place his unconscious self ( Na-khud ) (i.e. animalism).
And these are the meanings of egotism which is called as the mother of all evils and is therefore, undesirable. An egotist sees only his own animal-self and nothing else. All his actions, efforts, talks, and character revolves around the axis of satisfying his animalistic passions and desires. He practically considers himself as an animal and does not recognize any goal in life except meeting his animalistic requirements.
In order to accomplish these base animalistic objectives considers himself as independent or renegade and justifies all his actions. His animal-self is the only thing which he considers something sacred and honorable. He demands every thing for his own sake, even truth and justice, which should back up his animalistic desires, and if they are not on his side, does not need such justice, rather gives himself the right to wage combat against them.
He even interprets and comments religious commands and obligations as he pleases, assigning authenticity to his own opinions and thinking, whereby the religious laws and obligations are supposed to adopt themselves in accordance with his whims and passions.
Since an egotist is deprived of real human dignity, virtues and moral perfection; he keeps himself amused with whimsical, false, and futile affairs such as: seeking false publicity, ambitiousness, covetousness, snobbishness, eating, drinking, sexual pleasures, and remains totally ignorant from God's Remembrance and self-perfection.